Mice Discover the Link Between Cat Stress and Comfort Food Cravings

Research reveals the role of Proenkephalin in emotional eating triggered by stress, highlighting potential pathways for therapeutic interventions.

Recent findings have shed light on how stress can trigger cravings for comfort foods, revealing a molecular player in this emotional eating phenomenon.

The familiar fight or flight response, which heightens heart rates and anxiety in the face of threats, is well understood.

However, the aftermath of these stressful moments often goes unnoticed, particularly when it comes to our food choices.

Understanding Emotional Eating

After navigating through stress, many people find themselves reaching for high-fat, processed foods that provide a fleeting sense of relief.

This behavior, aptly known as emotional eating, has attracted scientific interest, as it represents more than just a personal struggle; it’s a key area of investigation in psychology and neuroscience.

The Role of Proenkephalin

A significant breakthrough in this field has emerged from a research team led by Sora Shin, an assistant professor at the Fralin Biomedical Research Institute at Virginia Tech.

Their important findings were published in Nature Communications on October 28.

Shin emphasizes that eating isn’t driven solely by physical hunger—emotions and situational contexts play a crucial role as well.

The research focused on a particular molecule named Proenkephalin, which, while present throughout various brain regions, had not been thoroughly examined in terms of its function within the hypothalamus, a vital area for regulating hunger.

To delve into the connection between stress and eating habits, the research team set up experiments with mice.

They introduced the scent of cat feces—an instinctual threat to the rodents—to induce a stress response.

A day later, the mice demonstrated signs of distress and a marked increase in food intake, especially of high-fat options.

Their neurons exhibited enhanced sensitivity toward these types of foods.

Future Directions and Implications

To confirm the significance of Proenkephalin in the context of stress-related overeating, the researchers activated the neurons artificially using light, without any exposure to the predator’s scent.

This also led to increased consumption patterns among the mice.

On the contrary, when the team inhibited the activity of those specific neurons while the mice were exposed to the cat odor, the animals did not experience negative feelings or a rise in hunger.

Shin highlighted the pivotal role of Proenkephalin in understanding why people might overeat during stressful times.

This discovery opens promising new paths for therapeutic strategies aimed at curbing emotional eating that stems from stress.

While the research team has successfully identified a critical molecule and pinpointed its location within the brain, they recognize that more work is needed.

Future studies will be essential to unravel the full implications of this finding and its potential influence on managing emotional eating behaviors.

Source: ScienceDaily